Pokémon: Best Wishes! (ポケットモンスターベストウイッシュ!, Poketto Monsutā Besuto Uisshu!) is the 4th and newest series of the Pokémon anime. Pokémon: Best Wishes! in Japan, premiered in September 2010. TV Tokyo announced that the season will cover the main protagonist Ash Ketchum and his Pikachu's adventures in the new region Unova. As always, the past female companion of Ash, Dawn, has left the series, and is being replaced by a girl named Iris. Iris is revealed to have a Axew, who oddly, lives in her hair. For an unexpected change, Brock seems to have left the series permanently, and is replaced by a new boy named Cilan, who is also a Gym Leader. Team Rocket are still in the series, and new antagonists will appear in the form of crime syndicate Team Plasma. Team Plasma is after the Legendary Duo Reshiram and Zekrom, similar to how other villainous teams went after the Legendary Pokémon in their respective regions. Ash will also have a new set of clothing based on Pokémon Black and White's male player character's design.
This series is called Pocket Monsters: Best Wishes! in Japan. In short Pokémon BW (it also can be coined as Pokémon Black and White). Like every region, this region also has its own main legendary Pokémon duo Reshiram and Zekrom and an additional legendary Pokémon Victini is also introduced. Ash Ketchum starts off his journey (complete with a new outfit) to this new region along with his faithful companion Pikachu, leaving behind Brock and Dawn on their respective quests, and also the other Pokémon which he caught in the Sinnoh region back at Professor Oak's Lab. This time Ash is going to compete in the Unova League by gaining the eight badges of that region capturing and befriending new Pokémon along the way. It is still unknown how many seasons this 4th series will have. Iris and Cilan will be revealed respectively. It is still unknown regarding what their personal goals are as of now, though they will surely be revealed when Ash meets them in the series in due course. More information regarding the series will unravel as the series progresses.