The play tells the famous doctor of the Ming Dynasty Tan Yunxian with medical obsession and love to overcome difficulties, create and establish a female medical system, and ultimately become a generation of women's medical experience. Daming is prosperous state ethics women's low status, not harsh, medical conditions, refractory. Tan Jiawei medical family, several generations of ancestors are for physician, was a schemer framed and face extinction because of, from leaving the Zuxun, later shall not practice. But the Tan Yunxian wisdom of the small monasteries, secretly with grandma to learn the knowledge of traditional Chinese medicine, not only Xuanhujishi, MicroHand benevolence, ordinary people praise and support, more gradually save heart of woman in the world. Thus, Yoona and Seohyun not only in physic along the road to face numerous difficulties and obstacles, but also to in the face of the impact of feudal ethical code and secular ideas. But Yoona and Seohyun with obsession for medical career and love to overcome difficulties, not only in medicine widely on gambling, eclectic, faction, more breakthroughs harsh Confucianism fetter, initiated and established female medical system, from rescue body to save the soul, from rescue to save the nation, promote the spread of the traditional Chinese medicine culture, eventually become a generation of women in medicine and famous in the world.