A special military unit fights a powerful, out-of-control supercomputer and hundreds of scientists who have mutated into flesh-eating creatures after a laboratory accident.
A virus has escaped in a secret facility called "The Hive," turning the staff into hungry zombies and releasing the mutated Lab "Animals" that they were studying. The complex computer shuts down the base to prevent infection. The parent corporation sends in an elite military unit, where they meet Alice, who is suffering from amnesia due to exposure to nerve gas. The military team must shut down the computer and get out, fighting their way past zombies, mutants, and the computer itself, before the virus escapes and infects the rest of the world. Alice must also come to terms with her slowly-returning memories.

 umbrella company (Umbrella, Corporation) some terrible things are hidden in the huge underground lair of ---- "honeycomb" (the Hive) Genetic Research Center, gathered here with the mysterious bioengineer. The outbreak of a deadly virus, and quickly spread. "Red Queen" ---- one to control and monitor the whole "hive" super giant computer the center are closed up, and even a small loophole, "killed" all the staff were trapped inside . Alice (Alice, Milla - Jovovich ornaments) and Rennes (Rain, Michelle - Rodriguez ornaments) must lead the Task Force members who will destroy the umbrella of all researchers virus isolation. However, players soon discovered that these staff are not really dead. They are now wandering in the "hive" greed of the Living Dead zombie-like. People once they bite one or scratches can become infected, even immediately become their class. Alice and her contingent has three hours to complete their task, otherwise, these zombies will be flooded to pose a threat to the entire planet. Close to the Red Queen, the members of the squad must be like a honeycomb-like maze, through a series of one than a terrorist barriers. Including deadly laser, shaped dog claws and a huge sample house, seen in this sample house Alice to the umbrella of evil research contributed to the crisis. Alice soon found these zombies are the result of the company to a new research programs ---- variant of the T-virus. Initial design of the T-virus anti-aging treatment of neurological disease, it has the ability to activate the dead cells. Alice realized that this is certainly a mysterious vandals stole the virus and release it to the "honeycomb" air. This is the crisis passed. Who did it? Why do this? In the face of this giant computer, Rennes pretend Red Queen to help them. The Red Queen agrees, but insisted that those who are infected are not allowed to escape. Of course, unless they can first find the restraint of this virus, anti-virus. Effective way is to use a genetic variant of the test, is the use of well-known evil creatures ---- "lick" (Licker) can now destroy all the zombies. "Lick" each kill a man, his strength will increase, also the work of the Task Force more dangerous. The Task Force can be to defeat the Red Queen, to find within the time prescribed anti-virus? Or, if they will become a zombie? If it was alive to escape evil "honeycomb", then who would?