Meredith, shattered by revelation, is forced to work with Addison, Joe collapses at the bar, Cristina has some pretty shattering news of her own, and Alex starts working on Izzie.
Barowner Joe collapses in his bar and needs to undergo an 200.000$ surgery to survive. Since Joe has no inurance George tries to find a way to get the money together. Dr. Webber is recovering from his operation and appointed Burke as his replacement. Burke has now to face the conequences that come with the responibilities of his new position. The return of his wife Addison puts an end to Derek's relationhip with Meredith. Meredith herelf is more concerned with the pregnancy of Christina and her secret relationhip with Burke.

welcome to Grace Hospital, west of Harvard toughest surgical residency medical internship program, medical couple of the most brutal training ground . Meredith, to Izzie and Christina, yesterday was a student, today is the doctor if they can survive the Grace Hospital for seven years purgatory test, they will be able to become a qualified surgeon. however, placed in this three in front of the group, not only is hard practical training, they have to deal with jealous boyfriends and sick parents, a night of passion and the housing crisis. the face of numerous difficulties, they only rely on each other.
Shonda Rhimes - ntroducing , Dorothy Dandridge, the author - this tells us "When the doctor of the young woman" or that "is still the drama of a young woman doctor".