Kyousuke's younger sister Namika has been living apart from him for ten years. One day, she returns and begins to live with him again, but she has turned into an energetic Osaka girl.

Boku no Imōto wa "Ōsaka Okan" (僕の妹は「大阪おかん」, lit. My Little Sister's an "Osaka Momma") (officially stylized as Boku-no-imoutowa"Osaka-okan") is a 12-episode anime television series produced by Charaction and directed by Kōtarō Ishidate. It aired in Japan between December 21, 2012 and March 15, 2013 on BS Asahi. The series has been licensed for streaming by Crunchyroll.