smoke, the blanket of darkness, silence ... only five years, life filled the earth has become the land of the virus outbreak zombie rampage of destruction. Not a stranger near the brink of death in the world, Alice (Milla Jovovich) still refuses to give up their last hope. Why innocent people tortured those culprit of the "umbrella" company can be hiding in the underground to live and work, the vegetation is not scared? Is it ruins the end of the world, not even a way out of the sun? Searching for an Alice drove a small aircraft in Alaska's frozen wilderness, only to find the world has been one of the few in this land are not variants of the virus ravaged survivors.
Unconscious Claire (Elle lats) appear in the Alice in front, she could not believe my own eyes. Former comrades in arms of extremely powerful, not only bizarre memory total loss, chest went so far been implanted received a strange signal mechanism. Needless to say, "lay violent hands" is the the sinful umbrella company. The far north of Alaska, has fallen into the zombie hands, the world is no longer the safe area, now may be the only surviving, is to follow the strange signal deeper investigation to ferret out the culprit, one strike and death!
The signal leads them to Los Angeles. The great Hollywood signs, has now turned into rubble. Dilapidated Los Angeles, and everywhere is the Destruction of the decay traces. The deathly silence of the ruins, the endless variety of new zombie with supernatural power. Fortunately, Claire gradually restored memory and superior fighting power, Claire's brother, as the STARS Alpha team players Chris (Wentworth Miller) arrived in time, Alice has been a respite. About to start a World War II and the "umbrella" company, breaking all sorts of obstacles in depth venture will soon fall into the monster level of the Alpha squad captain Albert Wesker (Shawn Roberts), a death trap. Through the fog, Alice they discovered that behind all this is likely to hide the terror extremely terrible plot ...